In the Asia-Pacific region, Korea and China are implementing modern chemical management systems, informally known as K-REACH and China-REACH respectively. These systems are based upon the principles of EU REACH, under which chemicals need to be registered to the regulatory authorities with hazardous chemicals undergoing further assessment. Other countries in Asia, such as Taiwan, Malaysia, Thailand and Vietnam, are also developing chemical management systems.

The CI and other metals associations are working to ensure consistency in the approaches used in risk assessment with the approaches used for the EU REACH Registration dossiers, such as Weight of Evidence and grouping principles and metals-specific risk assessment methodologies.

In Australia, the National Industrial Chemicals Notification and Assessment Scheme (NICNAS) recently completed a review of many cobalt compounds under its Inventory Multi-Tiered Assessment and Prioritisation (IMAP) framework, to which the CI actively contributed.